IRIS
CAPPELLINI, Alessandra
 Distribuzione geografica
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Continente #
EU - Europa 1.692
NA - Nord America 1.472
AS - Asia 510
Continente sconosciuto - Info sul continente non disponibili 13
OC - Oceania 6
SA - Sud America 2
AF - Africa 1
Totale 3.696
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Nazione #
US - Stati Uniti d'America 1.468
IE - Irlanda 530
SE - Svezia 355
CN - Cina 247
DE - Germania 245
UA - Ucraina 237
IT - Italia 160
TR - Turchia 153
SG - Singapore 66
FI - Finlandia 65
GB - Regno Unito 48
BE - Belgio 19
VN - Vietnam 16
IN - India 15
EU - Europa 13
FR - Francia 12
HK - Hong Kong 6
AU - Australia 5
RU - Federazione Russa 4
CA - Canada 3
JP - Giappone 3
NL - Olanda 3
PL - Polonia 3
RO - Romania 3
CZ - Repubblica Ceca 2
DK - Danimarca 2
LU - Lussemburgo 2
AT - Austria 1
BR - Brasile 1
CL - Cile 1
GR - Grecia 1
KR - Corea 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
NZ - Nuova Zelanda 1
PA - Panama 1
SA - Arabia Saudita 1
ZA - Sudafrica 1
Totale 3.696
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Città #
Dublin 530
Chandler 366
Jacksonville 181
Izmir 150
Rome 93
Boardman 88
Ann Arbor 79
Wilmington 77
Nanjing 73
Woodbridge 62
Lawrence 46
Princeton 46
Singapore 41
Brooklyn 37
Ashburn 29
Beijing 29
Ogden 29
Nanchang 28
Brandenburg 25
Bologna 23
Helsinki 23
Brussels 19
Dearborn 19
New York 18
Changsha 16
Dong Ket 16
Des Moines 14
Inglewood 14
Jiaxing 13
Orange 13
Hebei 12
Kunming 12
Milan 12
Tianjin 12
Falls Church 11
Los Angeles 11
San Francisco 10
Santa Clara 10
Seattle 9
Shenyang 9
Cassino 8
Munich 8
Verona 8
Lanzhou 7
Salerno 7
Fairfield 6
Hangzhou 6
Hong Kong 6
Pune 6
Haikou 5
Ningbo 4
Changchun 3
Hanover 3
Norwalk 3
Tappahannock 3
Tokyo 3
Toronto 3
Zhengzhou 3
Auburn Hills 2
Cambridge 2
Canberra 2
Frankfurt am Main 2
Houston 2
Jinan 2
Katowice 2
Kocaeli 2
Luxembourg 2
Melbourne 2
Olomouc 2
Redwood City 2
Saint Petersburg 2
Walnut 2
Washington 2
Almaty 1
Amsterdam 1
Athens 1
Auckland 1
Bengaluru 1
Berlin 1
Bonndorf 1
Centurion 1
Clearwater 1
Copenhagen 1
Fuzhou 1
Groningen 1
Guangzhou 1
Hefei 1
Langfang 1
Las Vegas 1
London 1
Philadelphia 1
Phoenix 1
Redmond 1
Riyadh 1
Rotherham 1
San Diego 1
San Jose 1
Shaoxing 1
Shenzhen 1
Taizhou 1
Totale 2.454
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Nome #
Cytotoxic activity of the casein kinase 2 inhibitor CX-4945 against T-cell acute lymphoblastic leukemia: targeting the unfolded protein response signaling 150
Erucylphosphohomocholine, the first intravenously applicable alkylphosphocholine, is cytotoxic to acute myelogenous leukemia cells through JNK- and PP2A-dependent mechanisms. 124
The Akt/mammalian target of rapamycin signal transduction pathway is activated in high-risk myelodysplastic syndromes and influences cell survival and proliferation. 123
Caspase-dependent cleavage of 170-kDa P-glycoprotein during apoptosis of human T-lymphoblastoid CEM cells. 106
The cyclin-dependent kinase inhibitor roscovitine and the nucleoside analog sangivamycin induce apoptosis in caspase-3 deficient breast cancer cells independent of caspase mediated P-glycoprotein cleavage: implications for therapy of drug resistant breast cancers. 104
Caspase-9 is the upstream caspase activated by 8-methoxypsoralen and ultraviolet-A radiation treatment of Jurkat T leukemia cells and normal T lymphocytes 98
Two hits are better than one: targeting both phosphatidylinositol3-kinase and mammalian target of rapamycin as a therapeuticstrategy for acute leukemia treatment 91
Supravital exposure to propidium iodide identifies apoptosis on adherent cells. 90
Deguelin, A PI3K/AKT inhibitor, enhances chemosensitivity of leukaemia cells with an active PI3K/AKT pathway 89
Synergistic induction of apoptosis in human leukemia T cells by the Akt inhibitor perifosine and etoposide through activation of intrinsic and Fas-mediated extrinsic cell death pathways. 88
Metabolism and signaling activities of nuclear lipids. 88
Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor perifosine in acute myelogenous leukemia cells 88
The novel Akt inhibitor, perifosine, induces caspase-dependent apoptosis and downregulates P-glycoprotein expression in multidrug-resistant human T-acute leukemia cells by a JNK-dependent mechanism. 88
Widespread impairment of cell proliferation in the neonate Ts65Dn mouse, a model for Down syndrome. 85
Diacylglycerol kinase-theta is localized in the speckle domains of the nucleus. 84
HIV-1 Tat protects CD4+ Jurkat T lymphoblastoid cells from apoptosis mediated by TNF-related apoptosis-inducing ligand 84
A combination of temsirolimus, an allosteric mTOR inhibitor, with clofarabine as a new therapeutic option for patients with acute myeloid leukemia. 84
Flow cytometric detection of total and serine 473 phosphorylated Akt. 84
Detection of serine 473 phosphorylated Akt in acute myeloid leukaemia blasts by flow cytometry 84
Intranucleolar localization of DNA topoisomerase IIalpha is a distinctive feature of necrotic, but not of apoptotic, Jurkat T-cells. 83
Radiobiologic response of medulloblastoma cell lines: involvement of beta-catenin? 83
Synergistic cytotoxic effects of bortezomib and CK2 inhibitor CX-4945 in acute lymphoblastic leukemia: turning off the prosurvival ER chaperone BIP/Grp78 and turning on the proapoptotic NF-κB 83
Targeting Signaling Pathways in T-cell acute lymphoblastic leukemia initiating cells 81
PI3K paninhibition impairs more efficiently proliferation and survival of T-cell acute lymphoblastic leukemia cell lines when compared to isoform-selective PI3K inhibitors 81
Multidrug resistance-associated protein 1 expression is under the control of the phosphoinositide 3 kinase/Akt signal transduction network in human acute myelogenous leukemia blasts. 81
Phosphoinositide 3-kinase/Akt involvement in arsenic trioxide resistance of human leukemia cells. 80
Nuclear diacylglycerol kinase-theta is activated in response to nerve growth factor stimulation of PC12 cells. 80
The phosphoinositide 3-kinase/Akt pathway regulates cell cycle progression of HL60 human leukemia cells through cytoplasmic relocalization of the cyclin-dependent kinase inhibitor p27(Kip1) and control of cyclin D1 expression. 80
Constitutively active Akt1 protects HL60 leukemia cells from TRAIL-induced apoptosis through a mechanism involving NF-kappaB activation and cFLIP(L) up-regulation. 79
The emerging role of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in normal myelopoiesis and leukemogenesis. 79
The phosphoinositide 3-kinase/AKT1 pathway involvement in drug and all-trans-retinoic acid resistance of leukemia cells. 78
Therapeutic targeting of Polo-like kinase-1 and Aurora kinases in T-cell acute lymphoblastic leukemia 78
Molecular characterization of protein kinase C-alpha binding to lamin A. 78
Antiapoptotic role of p38 mitogen activated protein kinase in Jurkat T cells and normal human T lymphocytes treated with 8-methoxypsoralen and ultraviolet-A radiation. 77
The controversial nuclear matrix: a balanced point of view. 77
Application of flow cytometry to molecular medicine: detection of tumor necrosis factor-related apoptosis-inducing ligand receptors in acute myeloid leukaemia blasts. 74
Improving nelarabine efficacy in T cell acute lymphoblastic leukemia by targeting aberrant PI3K/AKT/mTOR signaling pathway 73
Advances in understanding the acute lymphoblastic leukemia bone marrow microenvironment: From biology to therapeutic targeting 73
Targeting the liver kinaseB1/AMP-activated protein kinasepathway as a therapeutic strategyfor hematological malignancies 72
Enhancing radiosensitivity of melanoma cells through very high dose rate pulses released by a plasma focus device. 71
Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor (2S)-1-(1H-Indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan2-amine (A443654) in T-cell acute lymphoblastic leukemia. 68
Phosphatidylinositol 3-kinase inhibition potentiates glucocorticoid response in B-cell acute lymphoblastic leukemia. 68
Involvement of the phosphoinositide 3-kinase/Akt signaling pathway in the resistance to therapeutic treatments of human leukemias. 61
Nuclear translocation of PKC-α is associated with cell cycle arrest and erythroid differentiation in myelodysplastic syndromes (MDSs) 58
Therapeutic targeting of CK2 in acute and chronic leukemias 58
Therapeutic potential of targeting mTOR in T-cell acute lymphoblastic leukemia (Review) 54
Totale 3.840
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Categoria #
all - tutte 16.763
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 16.763
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020238 0 0 0 0 5 63 22 57 6 12 69 4
2020/2021408 55 4 62 49 1 54 5 47 1 53 9 68
2021/2022345 7 4 1 26 35 9 7 34 10 17 69 126
2022/20231.568 103 145 57 154 87 261 0 93 622 5 17 24
2023/2024207 24 16 19 3 6 13 26 16 58 4 2 20
2024/2025143 24 12 44 9 54 0 0 0 0 0 0 0
Totale 3.840