Viral hepatitis B is a highly prevalent disease in the population, and represents an occupational risk for health care workers, frequently exposed to blood or other biological fluids. Vaccination with recombinant vaccines has allowed for widespread vaccination campaigns, particulary targetted to health care workers who are at risk. Nevertheless, there is a small percentage of subjects that produce few HBV protective antibody (<10 mIU/ml). In this review the authors consider the genetic (HLA), constitutional (sex, age, obesity), behavioural (smoke) and disease (kidney failure, AIDS) factors associated in the scientific literature with non-responders to hepatitis B vaccination.
Hepatitis B occupational risk for health care workers: Vaccination and non-responders
Capelli G.;
1996-01-01
Abstract
Viral hepatitis B is a highly prevalent disease in the population, and represents an occupational risk for health care workers, frequently exposed to blood or other biological fluids. Vaccination with recombinant vaccines has allowed for widespread vaccination campaigns, particulary targetted to health care workers who are at risk. Nevertheless, there is a small percentage of subjects that produce few HBV protective antibody (<10 mIU/ml). In this review the authors consider the genetic (HLA), constitutional (sex, age, obesity), behavioural (smoke) and disease (kidney failure, AIDS) factors associated in the scientific literature with non-responders to hepatitis B vaccination.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
