Information and Metabolism in Bacterial Chemotaxis

One of the most important issues in theoretical biology is to understand how control mechanisms are deployed by organisms to maintain their homeostasis and ensure their survival. A crucial issue is how organisms deal with environmental information in a way that ensures appropriate exchanges with the environment—even in the most basic of life forms (namely, bacteria). In this paper, I present an information theoretic formulation of how Escherichia coli responds to environmental information during chemotaxis and, more generally, a cybernetic model of the relationship between information and biophysical (metabolic) dynamics.